A validated pharmaceutical cold box with a signal-green status light in a dark cold-storage room

Engineered with Mega Fortris

Pharmaceutical Cold Chain · Vaccines · Biologics · Specialty Drugs

When medicine is the cargo, a few degrees decide everything.

Live temperature, humidity, light, shock and location for every pallet, parcel and cold box. Catch an excursion while the product can still be saved, not after it's written off at the dock.

No installation required See how it works →

Deploy · Detect · Direct Confidence in every movement.

01 · The stakes

A broken cold chain doesn't damage the medicine. It destroys it.

$35B

Lost worldwide each year to pharmaceutical cold-chain failures.

50%

Of vaccines wasted globally. Inadequate temperature control is a leading cause.

1–2°C

Enough deviation to degrade a biologic, vaccine or insulin dose beyond use.

85%+

Of biologics require cold storage. The fastest-growing, most fragile cargo there is.

Sources: WHO; IQVIA; pharmaceutical cold-chain market analyses, 2025.

Frosted glass vaccine vials in a steel tray inside a laboratory freezer

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02 · The rules

Temperature control isn't best practice. It's a condition of doing business.

EU Good Distribution Practice Continuous monitoring with calibrated equipment, excursion alarms and qualified lanes. Readings every 15–30 minutes.

Global WHO Annex 9 The model standard for time- and temperature-sensitive products, end to end: monitoring, calibration, controlled transport.

US FDA Storage Bands CRT 20–25°C, refrigerated 2–8°C, frozen ≤ −20°C. Ultra-cold and cryogenic for biologics.

Air IATA CEIV Pharma Temperature mapping and a documented compliance trail, audited against IATA's Temperature Control Regulations.

The instrument standard is calibrated and traceable. iMSense is EN 12830 certified, accurate to ±0.5°C, with data exportable for GDP and quality audits.

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A temperature-controlled air-cargo pharma container on a sunlit airport apron

03 · Customs & chain of custody

At the border, the clock and the cold chain run against each other.

Clearance is a cold-chain risk

WHO Annex 9 names port handling and customs as critical control points. The wait to clear is when temperature drifts.

An unbroken custody trail

Regimes like US DSCSA require an electronic, interoperable record every time custody changes hands.

Condition and custody, together

Did it stay in range, and who held it? iMSense answers both, on one continuous timeline.

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04 · Data logger vs real-time

A USB logger tells you the dose was lost. Too late to save it.

A rejected vaccine carton on a loading dock

Record-only data logger

Logs to memory, read at the destination. Every reading arrives too late. An excursion is discovered, never prevented.

Answers "What happened?" after the dose is already destroyed.

iMSense real-time logger

Streams temperature, humidity, light, shock and GPS live throughout the trip. An excursion becomes an alert in transit, in time to re-ice, re-route or intervene.

Answers "What's happening?" in time to act.

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05 · The solution

One real-time logger. Every range, from room temperature to cryogenic.

Deploy. Activate and drop in. No fitting, no integration.

Detect. Temperature, humidity, light, shock and location, 24/7.

Direct. Flag a drift toward the limit before it becomes an excursion.

iMSense V5 Cryo −200°C Cryogenic: mRNA vaccines, biologics, cell & gene

iMSense V5 Probe −40 to +80°C Product-core temperature, not just the air

iMSense V5 Pro ±0.5°C The all-round RTL: GPS, humidity, light, shock

iMSense

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06 · What you gain

Fewer destroyed shipments. Audit-ready proof for every one.

Catch excursions in transit

A live alert the moment temperature drifts, a box is opened or a cooler fails. Early enough to save the product, not destroy it.

Compliance you can prove

A continuous, time-stamped, calibrated record, including product-core temperature. It satisfies GDP, WHO, FDA and CEIV audits.

Protect the chain of custody

Live location plus open-event detection gives a defensible custody trail from pack-out to delivery. The proof customs and quality ask for.

One live view, every lane

Every shipment, cooler and exception on a single dashboard. Temperature, humidity, location and open-events, in real time, worldwide.

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07 · Platform & AI

The hardware sees it. The platform makes it act.

Live dashboard & mobile app

Every shipment, temperature trace and exception in one view. On the wall and in your pocket.

The GritCargo AI App

Flags risk before it breaches, automates GDP / CEIV reporting, and integrates with your ERP, TMS and quality systems.

GritCargo Dashboard showing a temperature trace, live route map and in-transit shipment

GritClaw agent chat flagging an unscheduled opening event

07

Sunrise over a pharmaceutical distribution hub with a temperature-controlled truck pulling away

The outcome

From "we'll find out on arrival" to "we already knew, and acted."

Plug-and-play, real-time visibility across every pharmaceutical movement, pack-out to patient-side. Compliant by record, defensible by data, recoverable by proof.

Request a pilot → support@gritcargo.com Start with a paid pilot on a live route.

gritcargo Confidence in every movement.

Engineered with Mega Fortris · gritcargo.com